These optical resonators provide an ideal platform for sensitive, robust and label-free biosensors due to their ability to detect changes in the effective refractive index of the surrounding medium. A primary objective of our research is to couple low background fluorescence imaging with microresonators to create a scalable biosensor with low detection limits. We aim to develop a multiplexed bioassay for early detection of ovarian cancer.
Using the same theory and phenomena as the whispering gallery mode imaging project, we hope to expand the applications of WGM imaging by investigating biosensors made of optical fibers and microresonators. Currently, we are exploring the use of fiber optic based prisms for launching WGMs in fluorescently coated microsphere resonators.
Compact Disc Diagnostics